2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007
CELL Program students are in bold.
Gao J, Cui JZ, To E, Cao S, Matsubara JA (2018) Evidence for the activation of pyroptotic and apoptotic pathways in RPE cells associated with NLRP3 inflammasome in the rodent eye. Journal of Neuroinflammation 15(1):15. doi: 10.1186/s12974-018-1062-3.
Garner SRC, Castellanos MC, Baillie KE, Lian T, Allan DW (2018) Drosophila female-specific Ilp7 motoneurons are generated by Fruitless-dependent cell death in males and by a double-assurance survival role for Transformer in females. Development 145(1). pii: dev150821. doi: 10.1242/dev.150821.
Goh GYS, Winter JJ, Bhanshali F, Doering KRS, Lai R, Lee K, Veal EA, Taubert S (2018) NHR-49/HNF4 integrates regulation of fatty acid metabolism with a protective transcriptional response to oxidative stress and fasting. Aging Cell 17(3):e12743. doi: 10.1111/acel.12743.
Krentz NAJ, Lee MYY, Xu EE, Sproul SLJ, Maslova A, Sasaki S, Lynn FC (2018) Single-Cell Transcriptome Profiling of Mouse and hESC-Derived Pancreatic Progenitors. Stem Cell Reports 11(6):1551-1564. doi: 10.1016/j.stemcr.
Lee AYL, Dubois CL, Sarai K, Zarei S, Schaeffer DF, Sander M, Kopp JL (2018) Cell of origin affects tumour development and phenotype in pancreatic ductal adenocarcinoma. Gut; pii: gutjnl-2017-314426. doi: 10.1136/gutjnl-2017-314426.
Lee JTC, Shanina I, Chu YN, Horwitz MS, Johnson JD (2018) Carbamazepine, a beta-cell protecting drug, reduces type 1 diabetes incidence in NOD mice. Scientific Reports 8(1):4588. doi: 10.1038/s41598-018-23026-w.
Neumann UH, Kwon MM, Baker RK, Kieffer TJ (2018) Leptin contributes to the beneficial effects of insulin treatment in streptozotocin-diabetic male mice. American Journal of Physiology-Endocrinology and Metabolism; doi: 10.1152/ajpendo.00159.
Wang EY, Cheng JC, Thakur A, Yi Y, Tsai SH, Hoodless PA (2018) YAP transcriptionally regulates ErbB2 to promote liver cell proliferation. Biochim Biophys Acta Gene Regul Mech pii: S1874-9399(18)30039-7. doi: 10.1016/j.bbagrm.
D’souza AM, Neumann UH, Glavas MM, Kieffer TJ (2017) The glucoregulatory actions of leptin. Molecular Metabolism 6,1052-1065.
D’souza AM, Kieffer TJ (2017) Restoration of Lepr in β cells of Lepr null mice does not prevent hyperinsulinemia and hyperglycemia. Molecular Metabolism 6, 585-593.
Fairchild MJ, Islam F, Tanentzapf G (2017) Identification of genetic networks that act in the somatic cells of the testis to mediate the developmental program of spermatogenesis. PLOS Genetics 13(9):e1007026.
Freeman SA, Christian S, Austin P, Iu I, Graves ML, Huang L, Tang S, Coombs D, Gold MR, Roskelley CD (2017) Applied stretch initiates directional invasion through the action of Rap1 GTPase as a tension sensor. Journal of Cell Science 130, 152-163.
Khong A, Kerr CH, Yeung CH, Keatings K, Nayak A, Allan DW, Jan E (2017) Disruption of stress granule formation by the multifunctional cricket paralysis virus 1A protein. Journal of Virology, doi: 10.1128/JVI.01779-16.
Krentz NAJ, van Hoof D, Li Z, Watanabe A, Tang M, Nian C, German MS, Lynn FC (2017) Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors. Developmental Cell 41(2):129-142.e6. doi: 10.1016/j.devcel.
Neumann UH, Ho JSS, Chen S, Tam YYC, Cullis PR, Kieffer TJ (2017) Lipid nanoparticle delivery of glucagon receptor siRNA improves glucose homeostasis in mouse models of diabetes. Molecular Metabolism 6, 1161-1172.
Templeman NM, Skovsø S, Page MM, Lim G, Johnson JD (2017) A causal role for hyperinsulinemia in obesity. Journal of Endocrinology; doi: 10.1530/JOE-16-0449.
Vent-Schmidt RY, Wen RH, Zong Z, Chiu CN, Tam BM, May CG, Moritz OL (2017) Opposing effects of valproic acid treatment mediated by histone deacetylase inhibitor activity in four transgenic X. laevis models of retinitis pigmentosa. Journal of Neuroscience 37, 1039-1054.
Adams A, Vogl AW High resolution localization of Rab5, EEA1 and nectin-3 to tubulobulbar complexes in the rat testis (2016) Anatomical Record (accepted, Ms# AR-16-0234).
Aharoni-Simon M, Shumiatcher R, Yeung A, Shih AZ, Dolinsky VW, Doucette CA, Luciani DS (2016) Bcl-2 regulates reactive oxygen species signaling and a redox-sensitive mitochondrial proton leak in mouse pancreatic β-cells. Endocrinology 157, 2270-2281.
Bond SR, Abramyan J, Fu K, Naus CC, Richman JM (2016). Pannexin 3 is required for late stage bone growth but not for initiation of ossification in avian embryo. Developmental Dynamics 245, 913-924.
Bround MJ, Wambolt R, Cen H, Asghari P, Albu RF, Han J, McAfee D, Pourrier M, Scott NE, Bohunek L, Kulpa JE, Chen SRW, Fedida D, Brownsey RW, Borchers CH, Foster LJ, Mayor T, Moore ED, Allard MF, Johnson JD (2016) Ryr2-mediated calcium signals specifically promote glucose oxidation via pyruvate dehydrogenase. Journal of Biological Chemistry 291, 23490-23505.
Campbell S, Hoffman BG (2016) Chromatin regulators in pancreas development and diabetes. Trends in Endocrinology and Metabolism 27, 142-152.
Cao S, Wang JC, Gao J, Wong M, To E, White VA, Cui JZ, Matsubara JA (2016) CFH Y402H polymorphism and the complement activation product C5a: effects on NF-κB activation and inflammasome gene regulation. British Journal of Ophthalmology 100, 713-718.
Chow LN, Schreiner P, Ng BY, Lo B, Hughes MR, Scott RW, Gusti V, Lecour S, Simonson E, Manisali I, Barta I, McNagny KM, Crawford J, Webb M, Underhill TM (2016) Impact of a CXCL12/CXCR4 antagonist in bleomycin (BLM) induced pulmonary fibrosis and carbon tetrachloride (CCl4) induced hepatic fibrosis in mice. PLoS One 11:e0151765.
D’Souza A, Johnson JD, Clee SM, Kieffer TJ (2016) Suppressing hyperinsulinemia prevents obesity but causes rapid onset of diabetes in leptin-deficient ob/ob mice. Molecular Metabolism 5, 1103-1112.
Denroche HC, Glavas MM, Tudurí E, Karunakaran S, Quong WL, Philippe M, Britton HM, Clee SM, Kieffer TJ (2016) Disrupted leptin signaling in the lateral hypothalamus and ventral premammillary nucleus alters insulin and glucagon secretion and protects against diet-induced obesity. Endocrinology 157, 2671-2685.
Denroche HC, Kwon MM, Glavas MM, Tuduri E, Philippe M, Quong WL, Kieffer TJ (2016) The role of autonomic efferents and uncoupling protein 1 in the glucose-lowering effect of leptin therapy. Molecular Metabolism. 5, 716-724.
Dionne DA, Skovsø S, Templeman NM, Clee SM, Johnson JD (2016) Caloric restriction paradoxically increases adiposity in mice with genetically reduced insulin. Endocrinology 157, 2724-2734.
D’Souza AM, Johnson JD, Clee SM, Kieffer T (2016) Suppressing hyperinsulinemia prevents obesity but causes rapid onset of diabetes in leptin-deficient Lep ob/ob mice. Molecular Metabolism 5, 1103-1112.
Fairchild MJ, Yang L, Goodwin K, Tanentzapf G (2016) Occluding junctions maintain stem cell niche homeostasis in the fly testis. Current Biology 26, 2492–2499.
Goodwin K, Ellis SJ, Lostchuck E, Zulueta-Coarasa T, Fernandez-Gonzalez R, Tanentzapf G (2016) Basal cell-extracellular matrix adhesion regulates force transmission during tissue morphogenesis. Developmental Cell 39, 611-625.
Graves ML, Cipollone JA, Austin P, Bell EM, Nielsen JS, Gilks CB, McNagny KM, Roskelley CD (2016) The cell surface mucin podocalyxin regulates collective breast tumor budding. Breast Cancer Research 18:11, doi: 10.1186/s13058-015-0670-4.
Grist SM, Nasseri SS, Poon T, Roskelley C, Cheung KC (2016) On-chip clearing of assays of 3-D cell cultures and micro-tissues. Biomicrofluidics, 10:044107.
Holmes WR, Edelstein-Keshet L (2016) Analysis of a minimal Rho-GTPase circuit regulating cell shape. Physical Biology 13, 046001.
Holmes WR, Golding AE, Bement WM, Edelstein-Keshet L (2016) A mathematical model of GTPase pattern formation during single-cell wound repair. Royal Society Interface Focus 6, 20160032.
Khademolhosseini F, Liu CC, Lim CJ, Chiao M (2016) Magnetically actuated microstructured surfaces can actively modify cell migration behavior. Biomedical Microdevices 18, 13.
Kramer JL, Minhas NK, Jutzeler CR, Erskine EL, Liu LJ, Ramer MS (2016) Neuropathic pain following traumatic spinal cord injury: Models, measurement, and mechanisms. Journal of Neuroscience Research, doi: 10.1002/jnr.23881.
Lee K, Goh GYS, Wong MA, Klassen TL, Taubert S (2016) Gain-of-function alleles in Caenorhabditis elegans nuclear hormone receptor nhr-49 are functionally distinct. PLoS One 11(9):e0162708.
López-Ceballos P, Herrera-Reyes AD, Coombs D, Tanentzapf G (2016) In vivo regulation of integrin turnover by outside-in activation. Journal of Cell Science 129, 2912-2924.
Mathew MD, Mathew ND, Miller A, Simpson M, Au V, Garland S, Gestin M, Edgley ML, Flibotte S, Balgi A, Chiang J, Giaever G, Dean P, Tung A, Roberge M, Roskelley C, Forge T, Nislow C, Moerman D (2016) Using C. elegans forward and reverse genetics to identify new compounds with anthelmintic activity. PLoS Neglected Tropical Diseases 10, e0005058.
Naus CC, Aftab Q, Sin WC (2016) Common mechanisms linking connexin43 to neural progenitor cell migration and glioma invasion. Seminars in Cell and Developmental Biology, 50, 59-66.
Neumann UH, Denroche HC, Mojibian M, Covey SD, Kieffer TJ (2016) Insulin knockout mice have extended survival but volatile blood glucose levels on leptin therapy. Endocrinology 157, 1007-1012.
Neumann UH, Ho JSS, Mojibian M, Covey SD, Charron MJ, Kieffer TJ (2016) Glucagon receptor gene deletion in insulin knockout mice modestly reduces blood glucose and ketones but does not promote survival. Molecular Metabolism 5, 731-736.
Oudhoff MJ, Bream MJ, Freeman SA, Wong D, Rattray DG, Wang J, Antignano F, Snyder K, Rafaeli I, Hughes MR, McNagny KM, Gold MR, Arrowsmith CH, Sato T, Rossi FM, Tatlock JH, Owen DR, Brown PJ, Zaph C (2016) SETD7 controls intestinal regeneration and tumorigenesis by regulating Wnt/β-catenin and Hippo/YAP signaling. Developmental Cell 37, 47-57.
Porubský D, Sanders AD, van Wietmarschen N, Falconer E, Hills M, Spierings DC, Bevova MR, Guryev V, Lansdorp PM (2016) Direct chromosome-length haplotyping by single-cell sequencing. Genome Research 26, 1565-1574.
Sanders AD, Hills M, Porubský D, Guryev V, Falconer E, Lansdorp PM (2016) Characterizing polymorphic inversions in human genomes by single-cell sequencing. Genome Research 26, 1575-1587.
Scott RW, Underhill TM (2016) Methods and strategies for lineage tracing of mesenchymal progenitor cells. Methods in Molecular Biology 1416, 171-203.
Shin JJ, Aftab Q, Austin P, McQueen JA, Poon T, Li SC, Young BP, Roskelley CD, Loewen CJ (2016) Systematic identification of genes involved in metabolic acid stress resistance in yeast and their potential as cancer targets. Disease Models and Mechanisms 9, 1039-1049.
Sin WC, Aftab Q, Bechberger J, Leung J, Chen H, Naus CC (2016) Astrocytes promote glioma invasion via the gap junction protein connexin43. Oncogene 35, 1504-1516.
Speckmann T, Sabatini PV, Nian C, Smith RG, Lynn FC (2016) Npas4 transcription factor expression Is regulated by calcium signaling pathway and prevents tacrolimus-induced cytotoxicity in pancreatic beta cells. Journal of Biological Chemistry 291, 2682-2695.
Szabat M, Page MM, Panzhinskiy E, Skovsø S, Mojibian M, Fernandez-Tajes J, Bruin JE, Bround MJ, Lee JT, Xu EE, Taghizadeh F, O’Dwyer S, van de Bunt M, Moon KM, Sinha S, Han J, Fan Y, Lynn FC, Trucco M, Borchers CH, Foster LJ, Nislow C, Kieffer TJ, Johnson JD (2016) Reduced insulin production relieves endoplasmic reticulum stress and induces β cell proliferation. Cell Metabolism 23, 179-193.
Templeman NM, Mehran AE, Hu X, Johnson JD (2016) Hyper-variability in circulating insulin and physiological outcomes in male high fat-fed Ins1-/-:Ins2+/- mice in a specific pathogen-free facility. PLoS One; http://dx.doi.org/10.1371/journal.pone.0153280.
Tennant B, Vanderkruk B, Dhillon J, Dai D, Verchere B, Hoffman BG (2016) Myt3 suppression sensitizes islet cells to high glucose-induced cell death via Bim induction. Cell Death and Disease 7, e2233.
Tham DK, Joshi B, Moukhles H (2016) Aquaporin-4 cell-surface expression and turnover are regulated by dystroglycan, dynamin, and the extracellular matrix in astrocytes. PLoS One 11, e0165439.
Timbers TA, Garland SJ, Mohan S, Flibotte S, Edgley M, Muncaster Q, Au V, Li-Leger E, Rosell FI, Cai J, Rademakers S, Jansen G, Moerman DG, Leroux MR (2016) Accelerating gene discovery by phenotyping whole-genome sequenced multi-mutation strains and using the sequence kernel association test (SKAT). PLoS Genetics 12, e1006235
Vent-Schmidt RY, Wen RH, Zong Z, Chiu CN, May CG, Tam BM, Moritz OL (2016) Opposing effects of valproic acid treatment mediated by histone deacetylase inhibitor activity in four transgenic X. laevis models of retinitis pigmentosa. Journal of Neuroscience 1647-16.2016.
Whitfield ST, Burston HE, Bean BD, Raghuram N, Maldonado-Báez L, Davey M, Wendland B, Conibear E (2016) The alternate AP-1 adaptor subunit Apm2 interacts with the Mil1 regulatory protein and confers differential cargo sorting. Molecular Biology of the Cell 27, 588-598.
Adams WK, Sussman JL, Kaur S, D’Souza AM, Kieffer TJ, Winstanley CA (2015) Long-term, calorie-restricted intake of a high-fat diet in rats reduces impulse control and ventral striatal D2 receptor signalling – two markers of addiction vulnerability. European Journal of Neuroscience 42, 3095-3104.
Aftab Q, Sin WC, Naus CC (2015) Reduction in gap junction intercellular communication promotes glioma migration. Oncotarget 6:11447-11464.
Albrecht T, Zhao Y, Nguyen TH, Campbell RE, Johnson JD (2015) Fluorescent biosensors illuminate calcium levels within defined beta-cell endosome subpopulations. Cell Calcium 57, 263-274.
Berndt AJ, Tang JC, Ridyard MS, Lian T, Keatings K, Allan DW (2015) Gene regulatory mechanisms underlying the spatial and temporal regulation of target-dependent gene expression in Drosophila neurons. PLoS Genetics 11:e1005754.
Bogéa TH, Wen RH, Moritz OL (2015) Light induces ultrastructural changes in rod outer and inner segments, including autophagy, in a transgenic Xenopus laevis P23H rhodopsin model of retinitis pigmentosa. Investigative Ophthalmology & Visual Science 56, 7947-7955.
Dalton L, Davey M, Conibear E (2015) Large-scale analysis of membrane transport in yeast using invertase reporters. Methods Molecular Biology 1270, 395-409.
Denk F, Ramer LM, Erskine EL, Nassar MA, Bogdanov Y, Signore M, Wood JN, McMahon SB, Ramer MS (2015). Tamoxifen induces cellular stress in the nervous system by inhibiting cholesterol synthesis. Acta Neuropathologica Communications 3, 74.
Denroche HC, Kwon MM, Quong WL, Neumann UH, Kulpa JE, Karunakaran S, Clee SM, Brownsey RW, Covey SD, Kieffer TJ (2015) Leptin induces fasting hypoglycaemia in diabetic mice through the depletion of glycerol. Diabetologia 58, 1100-1108.
Ding W, Smulan LJ, Hou NS, Taubert S, Watts JL, Walker AK (2015) S-adenosylmethione levels govern innate immunity through distinct methylation-dependent pathways. Cell Metabolism 22, 633-645.
Fairchild MJ, Smendziuk C, Tanentzapf G (2015) A somatic permeability barrier around the germline is essential for Drosophila spermatogenesis. Development 142, 268-281.
Freeman SA, Jaumouillé V, Choi K, Hsu BE, Wong HS, Abraham L, Graves ML, Coombs D, Roskelley CD, Das R, Grinstein S, Gold MR (2015) Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor. Nature Communications 6, 6168. doi:10.1038/ncomms7168.
Gage BK Asadi A, Baker RK, Webber TD, Wang R, Itoh M, Hayashi M, Miyata R, Akashi T, Kieffer TJ (2015) The role of ARX in human pancreatic endocrine specification. PloS One 10, e0144100.
Gao J, Liu RT, Cao S, Cui JZ, Wang A, To E, Matsubara JA (2015) NLRP3 inflammasome: activation and regulation in age-related macular degeneration. Mediators of Inflammation 2015:690243. doi: 10.1155/2015/690243.
Garside VC, Cullum R, Alder O, Lu DY, Vander Werff R, Bilenky M, Zhao Y, Jones SJ, Marra MA Underhill TM, Hoodless PA (2015) SOX9 modulates the expression of key transcription factors required for heart valve development. Development 142, 4340-4350.
Grants JM, Goh GYS, Taubert S. (2015) The Mediator complex of Caenorhabditis elegans. Nucleic Acids Research 43, 2442-2453.
Hákonardóttir GK, López-Ceballos P, Herrera-Reyes AD, Das R, Coombs D, Tanentzapf G (2015) In vivo quantitative analysis of talin turnover in response to force. Molecular Biology of the Cell 26, 4149-4162.
Ho MM, Johnson JD, Clee SM (2015) PWD/PhJ mice have a genetically determined increase in nutrient-stimulated insulin secretion. Mammalian Genome 26, 131-141.
Holmes WR, Liao L, Bement B, Edelstein-Keshet L (2015) Modeling the role of protein kinase C eta and beta in single cell wound repair. Molecular Biology of the Cell 26, 4100-4108.
Hutter H, Moerman D (2015) Big data in Caenorhabditis elegans: quo vadis? Molecular Biology of the Cell 26, 3909-3914.
Kerr CH, Wang QS, Keatings K, Khong A, Allan D, Yip CK, Foster LJ, Jan E (2015) The 5′ untranslated region of a novel infectious molecular clone of the Dicistrovirus Cricket Paralysis Virus modulates infection. Journal of Virology 89, 5919-5934.
Konorov SO, Schulze HG, Gage BK, Kieffer TJ, Piret JM, Blades MW, Turner RF (2015) Process analytical utility of raman microspectroscopy in the directed differentiation of human pancreatic insulinpositive cells. Analytical Chemistry 87, 10762-10769.
Kwon MM, O’Dwyer SM, Baker RK, Covey SD, Kieffer TJ (2015) FGF21-mediated improvements in glucose clearance require uncoupling protein 1. Cell Reports 13, 1521-1527.
Li L, Gao G, Shankar J, Joshi B, Nabi IR (2015) p38MAP kinase regulation of Gp78 E3 ubiquitin ligase activity. Molecular Biology of the Cell 26, 3828-3840.
Liang X, Dong X, Moerman DG, Shen K, Wang X (2015) Sarcomeres pattern proprioceptive sensory dendritic endings through UNC-52/Perlecan in C. elegans. Developmental Cell 33, 388-400.
Lim GE, Albrecht T, Piske M, Sarai K, Lee JTC, Ramshaw HS, Sinha S, Guthridge MA, Acker-Palmer A, Lopez AF, Clee SM, Nislow C, Johnson JD (2015) 14-3-3z coordinates adipogenesis of visceral fat. Nature Communications 6, 7671. doi: 10.1038/ncomms8671.
Meng F, Joshi B, Nabi IR (2015) PTRF/Cavin-1 interacts with galectin-3 to control caveolin-1-dependent migration of PC3 prostate cancer cells. PLoS One 10, e0126056.
Nimmagadda S, Buchtova M, Fu K, Geetha-Loganathan P, Hosseini-Farahabadi S, Trachtenberg AJ, Kuo WP, Vesela I, Richman JM (2015) Identification and functional analysis of novel facial patterning genes in the duplicated beak chicken embryo. Developmental Biology 407, 275-288.
Racacho L, Byrnes AM, MacDonald H, Dranse HJ, Nikkel SM, Allanson J, Rosser E, Underhill TM, Bulman DE (2015) Two novel disease-causing variants in BMPR1B are associated with brachydactyly type A1. European Journal of Human Genetics 23, 1640-1645.
Sabatini PV, Lynn FC (2015) All-encomPASsing regulation of β-cells: PAS domain proteins in β-cell dysfunction and diabetes. Trends in Endocrinology and Metabolism 26, 49-57.
Sanders SS, Hou J, Sutton LM, Garside VC, Mui KK, Singaraja RR, Hayden MR, Hoodless PA (2015) Huntingtin interacting proteins 14 and 14-like are required for chorioallantoic fusion during early placental development. Developmental Biology 397, 257-266.
Smendziuk CM, Messenberg A, Vogl AW, Tanentzapf G (2015) Bi-directional gap junction-mediated soma-germline communication is essential for spermatogenesis. Development 142, 2598-2609.
Snyder KA, Hughes MR, Hedberg B, Brandon J, Hernaez DC, Bergqvist P, Cruz E, Po K, Graves ML, Turvey ME, Nielsen JS, Wilkins JA, McColl SR, Babcook JS, Roskelley CD, McNagny KM (2015) Podocalyxin enhances breast tumor growth and metastasis and is a target for monoclonal antibody therapy. Breast Cancer Research 17:46.
Szabat M, Modi H, Ramracheya R, Girbinger V, Chan F, Lee JTC, Piske M, Kamal S, Yang YHC, Welling A, Rorsman P, Johnson JD (2015) High-content screening identifies a role for Na+ channels in insulin production. Royal Society Open Science 2, 150306. doi: 10.1098/rsos.150306.
Tam BM, Yang LL, Bogėa TH, Ross B, Martens G, Moritz OL (2015) Preparation of Xenopus laevis retinal cryosections for electron microscopy. Experimental Eye Research 136, 86-90.
Templeman NM, Clee SM, Johnson JD (2015) Transient suppression of hyperinsulinemia in growing female mice provides long-term protection against obesity. Diabetologia 58, 2392-2402.
Tennant BR, Chen J, Shih AZ, Luciani DS, Hoffman BG (2015) Myt3 mediates laminin-V/integrin-β1-induced islet-cell migration via Tgfbi. Molecular Endocrinology 29, 1254-1268.
Tennant B, Hurley P, Gill A, Whiting C, Hoffman BG (2015) The TrxG complex mediates cytokine induced de novo enhancer formation in islets. PLoS One 10, e0141470.
Wang JC, Cao S, Wang A, To E, Law G, Gao J, Zhang D, Cui JZ, Matsubara JA (2015) CFH Y402H polymorphism is associated with elevated vitreal GM-CSF and choroidal macrophages in the postmortem human eye. Molecular Vision 21, 264-272.
Wang PTC, Garcin PO, Fu M, Masoudi M, Panté N, Nabi IR (2015) Autocrine motility factor regulates Gp78 ubiquitin ligase endoplasmic reticulum-mitochondria coupling. Journal of Cell Science 128, 2759-2765.
Xu EE, Krentz NA, Tan S, Chow SZ, Tang M, Nian C, Lynn FC (2015) SOX4 cooperates with neurogenin 3 to regulate endocrine pancreas formation in mouse models. Diabetologia 58, 1013-1023.
Yang YHC, Wills QF, Johnson JD (2015) A live-cell, high-content imaging survey of 206 endogenous factors across five stress conditions reveals context-dependent survival effects in mouse primary beta cells. Diabetologia 58, 1239-1249.
Zhao T, Gao J, Van J, To E, Wang A, Cao S, Cui JZ, Guo JP, Lee M, McGeer PL, Matsubara JA (2015) Age-related increases in amyloid beta and membrane attack complex: evidence of inflammasome activation in the rodent eye. Journal of Neuroinflammation 12, 121. doi: 10.1186/s12974-015-0337-1.
Agbaga MP, Tam BM, Wong JS, Yang LL, Anderson RE, Moritz OL (2014) Mutant ELOVL4 that causes autosomal dominant stargardt-3 macular dystrophy is misrouted to rod outer segment disks. Investigative Ophthalmology & Visual Science 55, 3669-3680.
Albu RF, Chan GT, Zhu M, Wong ETC, Taghizadeh F, Hu X, Mehran AE, Johnson JD, Gsponer J, Mayor T (2014) A feature analysis of lower solubility proteins in three eukaryotic systems. Journal of Proteomics 118, 21-38.
Alder O, Cullum R, Lee S, Kan AC, Wei W, Yi Y, Garside VC, Bilenky M, Griffith M, Morrissy AS, Robertson GA, Thiessen N, Zhao Y, Chen Q, Pan D, Jones SJ, Marra MA, Hoodless PA (2014) Hippo signaling influences HNF4A and FOXA2 enhancer switching during hepatocyte differentiation. Cell Reports 9, 261-271.
Asghari P, Scriven DR, Sanatani S, Gandhi SK, Campbell AI, Moore EDW (2014) Non-uniform and variable arrangements of ryanodine receptors within mammalian ventricular couplons. Circulation Research 115, 252-26.
Bond S, Naus CC (2014) The pannexins: past and present. Frontiers in Physiology 5, 58.
Cetera M, Ramirez-San Juan GR, Oakes PW, Lewellyn L, Fairchild MJ, Tanentzapf G, Gardel ML, Horne-Badovinac S (2014) Epithelial rotation promotes the global alignment of contractile actin bundles during Drosophila egg chamber elongation. Nature Communications 5:5511.
Chan MT, Lim GE, Skovsø S, Yang YHC, Albrecht T, Alejandro EU, Hoesli C, Piret JM, Warnock GL, Johnson JD (2014) Effects of insulin on human pancreatic cancer progression modeled in vitro. BMC Cancer 14, 814.
Chang AC, Garside VC, Fournier M, Smrz J, Vrljicak P, Umlandt P, Fuller M, Robertson G, Zhao Y, Tam A, Jones SJ, Marra MA, Hoodless PA, Karsan A (2014) A Notch-dependent transcriptional hierarchy promotes mesenchymal transdifferentiation in the cardiac cushion. Developmental Dynamics 243, 894-905.
Chao JT, Wong AKO, Tavassoli S, Young BP, Chruscicki A, Fang NN, Howe LJ, Mayor T, Foster LJ, Loewen CJR (2014) Polarization of the Endoplasmic Reticulum by ER-Septin Tethering. Cell 158, 620-632.
D’Souza AM, Asadi A, Johnson JD, Covey SD, Kieffer TJ (2014) Leptin deficiency in rats results in hyperinsulinemia and impaired glucose homeostasis. Endocrinology 155, 1268-1279.
Ellis SJ, Lostchuck E, Goult BT, Bouaouina M, Fairchild MJ, López-Ceballos P, Calderwood DA, Tanentzapf G (2014) The talin head domain reinforces integrin-mediated adhesion by promoting adhesion complex stability and clustering. PLoS Genetics 10(11):e1004756.
Falk L, Dang-Lawson M, Vega Pizzaro JL, Pournia F, Choi K, Jang C, Naus CC, Matsuuchi L (2014) Mutations of Cx43 that effect B cell spreading in response to BCR signaling. Biology Open 3, 185-194.
Gage BK, Baker RK, Kieffer TJ (2014) Overexpression of PAX4 reduces glucagon expression in differentiating hESCs. Islets 6(2):e29236.
Garaulet DL, Castellanos MC, Bejarano F, Sanfilippo P, Tyler DM, Allan DW, Sánchez-Herrero E, Lai EC (2014) Homeotic function of Drosophila Bithorax-complex miRNAs mediates fertility by restricting multiple Hox genes and TALE cofactors in the CNS. Developmental Cell 29, 635-648.
Goh GYS, Martelli KL, Parhar KS, Kwong AW, Wong MA, Mah A, Hou NS, Taubert S (2014) The conserved Mediator subunit MDT-15 is required for oxidative stress responses in C. elegans. Aging Cell 13, 70-79.
Ho MM, Hu X, Karunakaran S, Johnson JD, Clee SM (2014) Altered pancreatic growth and insulin secretion in WSB/EiJ mice. PLoS One 9(2):e88352.
Hou J, Wei W, Saund RS, Xiang P, Cunningham TJ, Yi Y, Alder O, Lu DY, Savory JG, Krentz NA, Montpetit R, Cullum R, Hofs N, Lohnes D, Humphries RK, Yamanaka Y, Duester G, Saijoh Y, Hoodless PA (2014) A regulatory network controls nephrocan expression and midgut patterning. Development 141, 3772-3781.
Hou NS, Gutschmidt A, Choi DY, Pather K, Shi X, Watts JL, Hoppe T, Taubert S (2014) Activation of the endoplasmic reticulum unfolded protein response by lipid disequilibrium without disturbed proteostasis in vivo. Proceedings of the National Academy of Sciences USA 111, E2271-E2280.
Hou NS, Taubert S (2014) Membrane lipids and the endoplasmic reticulum unfolded protein response: a complicated relationship. Worm 3(3):e962405-1-5.
Krentz NA, Nian C, Lynn FC (2014) TALEN/CRISPR-mediated eGFP knock-in add-on at the OCT4 locus does not impact differentiation of human embryonic stem cells towards endoderm. PLoS One 9(12):e114275.
Lahiri S, Chao JT, Tavassoli S, Wong AKO, Choudhary V, Young BP, Loewen CJR, Prinz WA (2014) A conserved endoplasmic reticulum membrane protein complex (EMC) facilitates phospholipid transfer from the ER to mitochondria. PLoS Biology 12:e1001969.
Leclair P, Lim CJ (2014) CD47-independent effects mediated by the TSP-derived 4N1K peptide. PLoS One 9(5):e98358.
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Young JS, Vogl AW (2012) Focal adhesion proteins zyxin and vinculin are co-distributed at tubulobulbar complexes. Spermatogenesis 2, 1-6.
Aiga M, Levinson JN, Yoshida E, Bamji SX (2011) N-cadherin and neuroligins cooperate to regulate synapse formation in hippocampal cultures. Journal of Biological Chemistry 286, 851-858.
Alejandro EU, Lim GE, Mehran AE, Hu X, Taghizadeh F, Pelipeychenko D, Baccarini M, Johnson JD (2011) Pancreatic beta-cell Raf-1 is required for glucose tolerance, insulin secretion and insulin 2 transcription. FASEB Journal 25, 3884-3895.
Bond SR, Lau A, Penuela S, Sampaio AV, Underhill TM, Laird DW, Naus CC (2011) Pannexin3 is a novel target for Runx2, expressed by osteoblasts and mature growth plate chondrocytes. Journal of Bone and Mineral Research 26, 2911-2922.
Chang AC, Fu Y, Garside VC, Niessen K, Chang L, Fuller M, Setiadi A, Smrz J, Kyle A, Minchinton A, Marra M, Hoodless PA, Karsan A (2011) Notch initiates the endothelial-to-mesenchymal transition in the atrioventricular canal through autocrine activation of soluble guanylyl cyclase. Developmental Cell 21, 288-300.
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Maltby S, Freeman SA, Gold MJ, Baker JH, Minchinton AI, Gold MR, Roskelley CD, McNagny KM (2011) Opposing roles for CD34 in B16 melanoma tumor growth alter early stage vasculature and late stage immune cell infiltration. PLoS One 6(4):e18160.
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Petit A, Sanders AD, Kennedy TE, Tetzlaff W, Glattfelder KJ, Dalley RA, Puchalski RB, Jones AR, Roskams AJ (2011) Adult spinal cord radial glia display a unique progenitor phenotype. PLoS One 6(9):e24538.
Pines M, Fairchild MJ, Tanentzapf G (2011) Distinct regulatory mechanisms control integrin adhesive processes during tissue morphogenesis. Developmental Dynamics 240, 36-51.
Ribeiro I, Yuan L, Tanentzapf G, Dowling JJ, Kiger A (2011) Phosphoinositide regulation of integrin trafficking required for muscle attachment and maintenance. PLoS Genetics 7(2):e1001295.
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Tham DKL, Moukhles H (2011) Regulation of Kir4.1 and AQP4 expression and stability at the basolateral domain of epithelial MDCK cells by the extracellular matrix. American Journal of Physiology: Renal Physiology 301, F396-409.
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Alejandro EU, Kalynyak TB, Taghizadeh F, Gwiazda KS, Rawstron EK, Jacob KJ, Johnson JD (2010) Acute insulin signaling in pancreatic beta-cells is mediated by multiple Raf1 dependent pathways. Endocrinology 151, 502-512.
Chiu CG, Griffith OL, Strugnell S, Nabi IR, Gown A, Walker B, Wiseman SM (2010) Diagnostic utility of galectin-3 in thyroid cancer. American Journal of Pathology 176, 2067-2081.
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Joshi B, Li L, Nabi IR (2010) A role for KAI1 in promotion of cell proliferation and mammary gland hyperplasia by the gp78 ubiquitin ligase. Journal of Biological Chemistry 285, 8830-8839.
Karamboulas K, Dranse H, Underhill TM (2010) Regulation of BMP-dependent chondrogenesis in early limb mesenchyme by TGFβ signals. Journal of Cell Science 123, 2068-2076.
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2009
Asghari P, Schulson M, Scriven DRL, Martens G, Moore EDW (2009) Axial tubules of rat ventricular myocytes form multiple junctions with the SR. Biophysical Journal 96, 4651-4660.
Chao JT, Foster LJ, Loewen CJ (2009) Identification of protein complexes with quantitative proteomics in S. cerevisiae. Journal of Visualized Experiments 4, pii:1225. doi: 10.3791/1225.
Cheung TYS, Fairchild MJ, Zarivach R, Tanentzapf G, Van Petegem F (2009) Crystal structure of the talin integrin binding domain 2. Journal of Molecular Biology 387, 787-793.
Chopra N, Yang T, Asghari P, Moore EDW, Huke S, et al. (2009) Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias. Proceedings of the National Academy of Sciences USA 106, 7636-7641.
Chou A, Boerkoel C, du Souich C, Rupps R (2009) Phenotypic and molecular characterization of a novel DCX deletion and a review of the literature. Clinical Genetics 76, 214-218.
Cina C, Theis M, Willecke K, Maass K, Bechberger JF, Naus CC (2009) Involvement of the C-terminal of Connexin43 in neuronal migration. Journal of Neuroscience 29, 2009-2021.
De Vuyst E, Doecrock E, De Bock M, Van Moorhem M, Lai CP, Yamasaki H, Naus CC, Evans WH, Leybaert L (2009) Calcium-activation and inactivation of ATP release via connexin43 hemichannels is controlled by a calmodulin-arachidonic acid-ROS/NO signaling cascade. Cell Calcium 46, 176-187.
Decrock E, De Vuyst E, Vinken M, Van Moorhem M, Vranckx K, Wang N, Van Laeken L, De Bock M, D’Herde K, Lai CP, Rogiers V, Evans WH, Naus CC, Leybaert L (2009) Connexin43 hemichannels contribute to the propagation of apoptotic cell death in a rat C6 glioma cell model. Cell Death & Differentiation 16, 151-163.
du Souich C, Chou A, Yin J, Oh T, Nelson TN, Hurlburt J, Arbour L, Friedlander R, McGillivray BC, Tyshchenko N, Rump A, Poskitt KJ, Demos MK, Van Allen MI, Boerkoel CF (2009) Characterization of a new X-linked mental retardation syndrome with microcephaly, cortical malformation, and thin habitus. American Journal of Medical Genetics A 149A, 2469-2478.
Eade KT, Allan DW (2009) Neuronal phenotype in the mature nervous system is maintained by persistent retrograde bone morphogenetic protein signaling. Journal of Neuroscience 29, 3852-3864.
Fairbank M, St-Pierre P, Nabi IR (2009) The complex biology of autocrine motility factor/phosphoglucose isomerase (AMF/PGI) and its receptor, the gp78/AMFR E3 ubiquitin ligase. Molecular Biosystems 5, 793-801.
Forestieri R, Merchant CE, de Voogd NJ, Matainaho T, Kieffer TJ, Andersen RJ (2009) Alotaketals A and B, sesterterpenoids from the marine sponge Hamigera species that activate the cAMP cell signaling pathway. Organic Letters 11, 5166-5169.
Gwiazda KG, Yang TLB, Lin Y, Johnson JD (2009) Effects of palmitate on ER and cytosolic Ca2+ homeostasis in beta-cells. American Journal of Physiology 296, E690-E701.
Lai CP, Bechberger J, Naus CC (2009) Panx2 as a novel growth suppressor in C6 glioma cells. Oncogene 28, 4402-4408.
Lajoie P, Kojic LD, Nim S, Li L, Dennis JW, Nabi IR (2009) Caveolin-1 regulation of dynamin-dependent, raft-mediated endocytosis of cholera toxin-B subunit occurs independently of caveolae. Journal of Cellular and Molecular Medicine 13, 3218-3225.
Luciani DS, Gwiazda KG, Yang TLB, Kalynyak TB, Bychkivska Y, Frey MHZ, Jeffrey KD, Sampaio AV, Underhill MT, Johnson JD (2009) Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death. Diabetes 58, 422-432.
Noël G, Tham DKL, Moukhles H (2009) Interdependence of laminin-mediated clustering of lipid rafts and the dystrophin complex in astrocytes. Journal of Biological Chemistry 284, 19694-19704.
Sin W-C, Moniz DM, Ozog MA, Tyler JE, Numata M, Church J (2009) Regulation of early neurite morphogenesis by the Na+/H+ exchanger NHE1. Journal of Neuroscience 29, 8946-8959.
Sun Y, Aiga M, Yoshida E, Humbert PO, Bamji SX (2009) Scribble interacts with β-catenin to regulate the localization of synaptic vesicles. Molecular Biology of the Cell 20, 3390-3400.
Tavassoli S, Chao JT, Loewen CJ (2009) A high-throughput method to globally study organelle morphology in S. cerevisiae. Journal of Visualized Experiments 2, pii:1224. doi: 10.3791/1224.
Young JS, Guttman JA, Vaid KS, Vogl AW (2009) Cortactin (CTTN), N-WASP (WASL) and clathrin (CLTC) are present at podosome-like tubulobulbar complexes in the rat testis. Biology of Reproduction 80, 153-161.
Young JS, Guttman JA, Vaid KS, Shahinian H, Vogl AW (2009) Tubulobulbar complexes are intercellular podosome-like structures that internalize intact intercellular junctions during epithelial remodeling events in the rat testis. Biology of Reproduction 80, 162-174.
Lin KB, Freeman SA, Zabetian S, Brugger H, Weber M, Lei V, Dang-Lawson M, Tse KW, Santamaria R, Batista FD, Gold MR (2008) The rap GTPases regulate B cell morphology, immune-synapse formation, and signaling by particulate B cell receptor ligands. Immunity 28, 75-87.
2007
Bates D, Sin W-C, Aftab Q, Naus CC (2007) Connexin43 enhances glioma invasion by a mechanism involving the carboxy terminus. Glia 55, 1554-1564.
Cina C, Bechberger JF, Ozog MA, Naus CC (2007) Expression of connexins in embryonic mouse neocortical development. Journal of Comparative Neurology 504, 298-313.
Hunt-Newbury R, Viveiros R, Johnsen R, Mah A, Anastas D, Fang L, Halfnight E, Lee D, Lin J, Lorch A, McKay S, Okada HM, Pan J, Schulz AK, Tu D, Wong K, Zhao Z, Alexeyenko A, Burglin T, Sonnhammer E, Schnabel R, Jones SJ, Marra MA, Baillie DL, Moerman DG (2007) High-throughput in vivo analysis of gene expression in Caenorhabditis elegans. PLoS Biology 5:e237.
Lai CPK, Bechberger JF, Thompson R, MacVicar B, Bruzzone R, Naus CC (2007) Tumour suppressive effects of Panx1 in C6 glioma cells. Cancer Research 67, 1545-1554.
Loewen CJ, Young BP, Tavassoli S, Levine TP (2007) Inheritance of cortical ER in yeast is required for normal septin organization. Journal of Cell Biology 179, 467–483.
McCoy ML, Zhou L, MacDonald G, Mueller CR, Roskelley CD (2007) Regulation of the BRCA1 promoter in ovarian surface epithelial cells and ovarian carcinoma cells. FEBS Letters 581, 1825-1833.
Nielsen JS, McCoy ML, Chelliah S, Vogl AW, Roskelley CD, McNagny KM (2007) The CD34-related molecule Podocalyxin is a potent inducer of microvillus formation. PLoS One 2:e237.