New CELL Faculty Member Profile – Nicole Krentz
Dr. Krentz is a recently appointed Assistant Professor in the Faculty of Pharmaceutical Sciences whose lab is located on the 6th floor of the Pharmaceutical Sciences Building at UBC.
Nicole is a graduate of the Cell and Developmental Biology PhD program at the University of British Columbia. Her thesis focused on cell cycle regulation of mouse and human pancreas development. For her first post-doc, Nicole trained at the Wellcome Centre for Human Genetics at the University of Oxford, where she studied coding variants that influence type 2 diabetes risk by impacting beta cell development. For her second post-doc, Nicole joined the Department of Pediatrics Endocrinology at Stanford University. There she continued to investigate diabetes-associated genes, with a particular focus on pleiotropic variants that impact multiple traits and phenotypes.
The Krentz lab combines developmental biology and human genetics to understand how metabolic cells normally develop and how defects in this process leads to disease. They use several approaches, including mouse models of organogenesis, genome editing, stem and progenitor cell differentiation to multiple lineages, and multi-omic analyses, to study the transcriptional regulation of cell fate determination in metabolic cells.
Click here to find out more about Dr. Krentz’s lab.
Welcome Dr. Krentz!